In the earlier post, we mentioned that Weight gain, Osteoporosis and Sex hormones changes are often the common symptoms that a Cushing Sydrome patient can experience.
So why does high level of Cortisol cause these symptoms?
To answer that we are going to give away the 1st souvenir from our trip and it will be "The Reasons Behind Weight Gain in Cushing Sydrome Patients".
1. Overeating
When Cortisol is release, it will inhibit insulin production to prevent Glucose from being stored. By doing that, immediate use of glucose can be favored. So when high levels of Cortisol is produce, it may cause one to overeat.
So when one overeats, he/she will have an excess of unused glucose and eventually, these glucose will be stored as body fats, which will lead to weight gain.
2. Increase in visceral fat storage
Not only that, high levels of Cortisol can caused visceral fat storage. This is done by mobilizing the triglycerides and moving them to the visceral fat cells. Visceral fat cells are found under the muscle, deep in the abdomen.
So when more fats are stored in the visceral fat cells, it will cause the patient to have fat accumulating under the abdomen. (Weight gain at waist area)
3. Increasing in appetite
Studies also shown that Cortisol may directly influence appetite and cravings by binding to hypothalamus receptors in the brain. It also can indirectly influences appetite by modulating other hormones and stress responsive factors known to stimulate appetite.
So are you guys happy with our 1st souvenir from the Adrenal Land? Hope you like it and STAY TUNE for the 2nd one! See ya soon! :)
Credits:
http://www.todaysdietitian.com/newarchives/111609p38.shtml