Friday, November 28, 2014

Reasons behind the symptoms!

HEY GUYS! We are finally back from collecting souvenirs in the Adrenal-Land! Really excited to share with you guys!

In the earlier post, we mentioned that Weight gain, Osteoporosis and Sex hormones changes are often the common symptoms that a Cushing Sydrome patient can experience.

So why does high level of Cortisol cause these symptoms?

To answer that we are going to give away the 1st souvenir from our trip and it will be "The Reasons Behind Weight Gain in Cushing Sydrome Patients".

1. Overeating 

When Cortisol is release, it will inhibit insulin production to prevent Glucose from being stored. By doing that, immediate use of glucose can be favored. So when high levels of Cortisol is produce, it may cause one to overeat.


So when one overeats, he/she will have an excess of unused glucose and eventually, these glucose will be stored as body fats, which will lead to weight gain.

2. Increase in visceral fat storage

Not only that, high levels of Cortisol can caused visceral fat storage. This is done by mobilizing the triglycerides and moving them to the visceral fat cells. Visceral fat cells are found under the muscle, deep in the abdomen.

So when more fats are stored in the visceral fat cells, it will cause the patient to have fat accumulating under the abdomen. (Weight gain at waist area)









3. Increasing in appetite

Studies also shown that Cortisol may directly influence appetite and cravings by binding to hypothalamus receptors in the brain. It also can indirectly influences appetite by modulating other hormones and stress responsive factors known to stimulate appetite.

 




So are you guys happy with our 1st souvenir from the Adrenal Land? Hope you like it and STAY TUNE for the 2nd one! See ya soon! :)

Credits:
http://www.todaysdietitian.com/newarchives/111609p38.shtml
hqvectors.com
www.illustrationsof.com
cane2.com





Monday, November 24, 2014

Basic Knowledge of Cortisol!

BELLO! (Minion Language: Hello) We are back for another post on Cushing Syndrome! :)

Previously, we mentioned that Cushing Syndrome is a collection of hormonal disorders caused by high levels of Cortisol.  Moreover, we talked about the different kinds of symptoms that one may experience when he/she is diagnosed with this diseases. 

So why high levels of cortisol will cause one to look like this?


But before that, we need to know how Cortisol hormone works!

All in all, cortisol works hand in hand with Epinephrine (adrenaline) to help the body with the "Fight or Flight" response.

Therefore, when our body faces stress, Cortisol will help Epinephrine to prep our body. This is done by increasing our heart rate and production of glucose. (Glucose = ENERGY)

By now, We believe your eyes are tired from all those reading and on account of that, we will stop here!
However, please look forward to read our next blog post! SEE YA!


Credits:

Saturday, November 22, 2014

What is happening to our adrenal glands? (Cushing syndrome)

Hi peeps! WE ARE BACK! :)

In the previous post, we briefly talked about the anatomy and functions of the adrenal gland. So in a nutshell, our adrenal glands have two structures that produces hormones to either help with our body functions (Adrenal Cortex) or in the ''Fight or Flight" system (Adrenal Medulla).

Since our Adrenal Glands produces hormones that are essential for us, what would happen to our body if the production of hormones go hay-wired? And with this, we come to the first adrenal gland disorder, which is known as Cushing Syndrome.

So what is Cushing Syndrome?
It is basically a collection of hormonal disorders caused by high levels of Cortisol.  As mentioned in the previous post, our Adrenal Cortex produces Corticosteroid hormones and one of them is hydrocortisone hormone (Cortisol).



What are the Symptoms of Cushing Disease?

  1. Weight gain, especially on the waist.
  2. Moon Face
  3. Extra fats found at the neck
  4. Buffalo bump
  5. Skin changes
  6. Mood changes
  7. Bone or muscle weakness
  8. Changes in sex hormones


      


We believed you guys will be thinking that why high levels of cortisol will cause Cushing Syndrome and also what causes the high levels Cortisol.

However, we shall be bad and leave your curiosity hanging! HEEHEE! :P So STAY TUNE!

Credits:
http://www.medicinenet.com/cushings_syndrome/page2.htm
http://www.webmd.com/a-to-z-guides/cushings-syndrome-topic-overview-2
http://www.nlm.nih.gov/medlineplus/ency/article/000410.htm
badtzmarucy831.wordpress.com
almost.thedoctorschannel.com
www.fotosearch.com

Friday, November 21, 2014

Welcome to the world of Adrenal Gland!


Hi peeps! Glad you guys are visiting our new blog on the Adrenal Gland! To start of, we will introduce the anatomy of our wonderful Adrenal Glands. :)

Firstly, where are our adrenal glands found? They are basically neighbors of our kidneys! 
In other words, they are found sitting on the top of our kidneys.

Even through our adrenal glands lives very far away from our hypothalamus (which is found in the brain), they are actually very good business partners and without any one of them, the business (our body) will face huge problems.

Our adrenal gland is made up of two structures that produces hormones: the adrenal cortex and the adrenal medulla.


Even through this two structures are found in the same gland, but the hormones that they produced perform different functions.






Adrenal Cortex
Corticosteroid hormones
Aldosterone hormone
Androgenic steroids
Hydrocortisone
Corticosterone

Sex hormones
Controls the body’s metabolism of fats, proteins and carbohydrates

Plays a part in the immune system and suppresses inflammatory reactions.

Maintains the blood volume and pressure by inhibiting the amount of sodium being excreted into urine.

Does not have a huge impact as it is overshadowed by other hormones such as estrogen and testosterone.

Adrenal Medulla
Epinephrine (adrenaline)
Norepinephrine (noradrenaline)
Increases the heart rate and the force of heart contractions.

Results in more blood flow to the muscles, brain and quickens the conversion of glycogen to glucose in the liver.

Helps epinephrine in responding to stress by increasing the vasoconstriction of blood vessels thus increasing blood pressure.

Please stay tune to our next blog post for more information about our adrenal gland! Look forward to see you again! :)

Credits:
http://umm.edu/programs/diabetes/health/endocrinology-health-guide/adrenal-glands 

http://www.endocrineweb.com/endocrinology/overview-adrenal-glands